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Description of US patent and its weakness Essay Example

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Description of US patent and its weakness

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In an ideal situation, these properties are tunable independently such that optimal materials can be designed with the aim of achieving a cellular response. Practically, mechanical rigidity and bioactivity are two properties that are hard to de-couple. For instance, examples from nanofilm biomaterials created through the LbL method controls rigidity via chemically cross-linking the network of polymers after assembly, while conference of bioactivity is done via surface adsorbed or film-embedded bio-molecules. When film bio-activation is preceded by cross-linking, the embedded bio-molecules could be rendered inaccessible to the cells they are in contact with, whereas when bio-activation is followed by cross-linking, bio-molecular loadings is limited at the surface of the film (Chow & Cheng 35). Thus, for the current approach to making polymer nanofilm coatings, bioactivity and mechanical rigidity of the coating are strongly and usually inversely coupled.Thus, it was important to develop an approach to nanofilm coatings with bioactivity and mechanical rigidity that as tunable independently. One of the strategies to this was surface cross-linking, in which formation of cross-links was confined to the polymer film’s surface region in order not to interfere with species that are bioactive in the interior of the film (Yasuda 129). Nano-particle templating was another strategy used, here, the nanofilm was created alongside spherical latex nano-particles with cross-linking chemically, to improve rigidity of the film and imbue it with porous morphology, while removing nano-particles through dissolution. In this case, the idea revolved around the creation of a polymer nanofilm by hardening the polymer portion using standard methods of cross-linking followed by filling pore spaces with bioactive species (Johal 55). Both of these activities were done to extents that could be controlled independently.In using each of these strategies, there were key questions regarding how much the film would be penetrated by various macromolecular particles and species. Using the cross-linking method, the polymer, is bound to cross-linking agents so that it adsorbs to the film but does not penetrate it, allowing for the formation of cross-links with polymers that were already adsorbed to the surface of the film (Yang et al. In this case, the most essential question was whether the formation of cross-links happened before penetration of the polymer

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Works Cited

Chow, Pierstorff. & Cheng, Ho. "Copolymeric Nanofilm Platform for Controlled and Localized Therapeutic Delivery." Acs Nano. 2.1 (2008): 33-40. Print.

Johal, Malkiat. Understanding Nanomaterials. Boca Raton: CRC Press, 2011. Print.

Kato, Takemura. Ishii, Takarai. Watanabe, Sugiyama. Hiramatsu, Nanba. & Nishikawa, Taniguchi. "Conducting Polymer Nanofilm Growth on a Nanoscale Linked-Crater Pattern Fabricated on an Al Surface." Journal of Vacuum Science & Technology A: Vacuum, Surfaces, and Films. 26.4 (2008): 824. Print.

Lee, Sunggyu. Materials in Biology and Medicine. Hoboken: CRC Press, 2012. Print.

Malvadkar, Hancock. Sekeroglu, King. Dressick, James. & Demirel, Michael. "An Engineered Anisotropic Nanofilm with Unidirectional Wetting Properties." Nature Materials. 9.12 (2010): 1023-1028. Print.

Moss, Steven. Growth, Evolution and Properties of Surfaces, Thin Films and Self-Organized Structures: Symposium Held November 27 December 1, 2000, Boston, Massachusetts, U.s.a. Warrendale, Pa: Materials Research Society, 2001. Internet resource.

Phelps, Jennifer. Nanofilm Biomaterials: Controlling Mechanical Rigidity and Bioactivity. New Haven: Yale University Printing Press, 2010. Print.

Phelps, Jennifer. Morisse, Susan. Hindié, Michael. Degat, Charles. Pauthe, Edward. & Peter, Van Tassel. "Nanofilm Biomaterials: Localized Cross-Linking to Optimize Mechanical Rigidity and Bioactivity." Langmuir: the ACS Journal of Surfaces and Colloids. 27.3 (2011): 1123-1130. Print.

Pritchard, Eleanor. Valentin, Thomas. Panilaitis, Bruce. Omenetto, Fiorenzo. & Kaplan, David. "Antibiotic-releasing Silk Biomaterials for Infection Prevention and Treatment." Advanced Functional Materials. 23.7 (2013): 854-861. Print.

Rudra, Jai. Dave, Komal. & Haynie, Donald. "Antimicrobial Polypeptide Multilayer Nanocoatings." Journal of Biomaterials Science, Polymer Edition. 17.11 (2006): 1301-1315. Print.

Silva, Lurdes. Costa, António. Freitas, Ana. Rocha-Santos, Teresa. & Duarte, Armando. "Polymeric Nanofilm-Coated Optical Fibre Sensor for Speciation of Aromatic Compounds." International Journal of Environmental Analytical Chemistry. 89.3 (2009): 183-197. Print.

Subbiah, Ramesh. Lee, Haisung. Veerapandian, Murugan. Sadhasivam, Sathya. Seo, Soo-won. & Yun, Kyusik. "Structural and Biological Evaluation of a Multifunctional Swcnt-Agnps-Dna/pva Bio-Nanofilm." Analytical and Bioanalytical Chemistry. 400.2 (2011): 547-560. Print.

Tretinnikov, Olivia. "IR Spectroscopic Study of the Effect of Polymer Nanofilm Thickness on Its Surface Density." Journal of Applied Spectroscopy. 75.1 (2008): 64-68. Print.

Van Tassel, Peter. "Nanotechnology in Medicine: Nanofilm Biomaterials." The Yale Journal of Biology and Medicine. 86.4 (2013): 527-36. Print.

Wittmer, Corinne. Multilayer Protein/polyelectrolyte Assemblies as Nanofilm Biomaterials. New Haven: Yale University Printing Press. 2009. Print.

Wittmer, Corinne. Phelps, Jennifer. Lepus, Christin. Saltzman, William. Harding, Martha. & Van Tassel Peter. "Multilayer Nanofilms as Substrates for Hepatocellular Applications." Biomaterials. 29.30 (2008): 4082-4090. Print.

Wu, Connie. Aslan, Seyma. Gand, Adeline. Wolenski, Joseph. & Pauthe, Emmanuel. "Porous Nanofilm Biomaterials via Templated Layer-by-Layer Assembly." Advanced Functional Materials. 23.1 (2013): 66-74. Print.

Yang, Xiudong. Jiang, Bo. Huang, Yi. Tian, Yunfei. Chen, Hong. Chen, Jiyong. & Yang, Bangcheng. "Collagen Nanofilm Immobilized on at Surfaces by Electrodeposition Method." Journal of Biomedical Materials Research Part B: Applied Biomaterials. 90.2 (2009): 608-613. Print.

Yasuda, Hirotsugu. "Biocompatibility of Nanofilm-Encapsulated Silicone and Silicone-Hydrogel Contact Lenses." Macromolecular Bioscience. 6.2 (2006): 121-138. Print.

Yasuda, Hirotsugu. Olcaytug, Ledernez. & Bergmann, Dame. "Biocompatible Nanofilm Coating by Magneto-Luminous Polymerization of Methane." Progress in Organic Coatings. 74.4 (2012): 667-678. Print.

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preview essay on Description of US patent and its weakness
  • Pages: 7 (1750 words)
  • Document Type: Essay
  • Subject: Chemistry
  • Level: Undergraduate
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