Thus, researchers have been able to produce colons from an engineered tissue and adult cells with 100% results22. The tissue-engineered colon showed an architecture similar to the original colon. The TEC’smuscularispropria stained for actin, had ganglion cells, and S100-positive cells.23 In anastomosis, the colon architecture was preserved24. The produced colon has been shown to have constant in vitro function just like that in mature colonocytes25. Thus, if a colon has been damaged by colon cancer, TEC could be used as an effective means to replace the impaired colon.
Under esophageal tissue engineering, studies note that acellular scaffolds can be transplanted with the goal of having the smooth muscle and epithelial cells move to populate the conduit in use once more26. These scaffolds include the collagen scaffolds that have been utilized to create porous tube-like structures27. However, their use presented limitations due to a lack of regrowth in the muscles27. Synthetic scaffolds have been utilized but have poor results in terms of the migration of the cells caused by the features of the materials28. Decellularised scaffolds emanating from the esophagus shown to produce mixed results29. The Applicability of TE in Cancer Treatment.
Please type your essay title, choose your document type, enter your email and we send you essay samples