The patient will be checked first for an official diagnosis of diabetes I or II, and will also be tested for muscular oxidative stress (mitochondria), and weakness of satellite cells, along with adrenal fatigue, will also be tested and measured. The patient is currently taking medication for depression, migraine and fibromyalgia.There are two widely-held hypotheses regarding the nature of CFS and associated illnesses commonly found with the overall diagnosis of CFS. The first is that fatigue is caused by psychological factors and that there is a lack of motivation and typical alertness, commonly found in healthy people (Johnson, 2013). While physical metabolism may be functioning properly, it can be assumed that low energy is caused more by stress and anxiety, tension and depression. The alternative is that it is a metabolic dysfunction, particularly in reference to faulty mitochondria oxidation of glucose to water and carbon dioxide (Myhill, Booth, & McLaren-Howard, 2009; NYT, 2008).The causes of the CFS are unknown, but certain studies have proposed that a defect within the energy producing element of muscle cells, known as mitochondria, may be responsible. Other studies, nonetheless, have not been capable of demonstrating this defect. It is believed that limitations in the approaches used to define mitochondrial function in the human muscle fibres may be the reason as to why causes of mitochondria dysfunction have been difficult to explore. Researchers anticipate developing a new method that will demonstrate if skeletal muscle mitochondria in victims of CFS are dysfunctional, that would result in the muscle fatigue and more complications leading to the chronic inflammation and pain. The mechanisms which lead to debilitating the muscle fatigue CFS patients are actually unknown (Alicia & Anibal, 2011). The time needed for diagnosis even complicates more the identification of factors responsible for triggering this illness. Scientists have theorized that mitochondria malfunction considerably reduce the energy supply to muscle cells which allow the body to perform its daily activities. The fatigue and inflammation which follows may cause further mitochondrial abnormalities hence the vicious cycle of the events continue.In every cell glucose is normally broken down to pyruvate accompanied with the generation of some ATP (two molecules net/molecule of glucose). Pyruvate and also the fatty acids enter mitochondria of every
ALICIA J. K & ANIBAL E. (2011). Mitochondrial damage induced by conditions of oxidative
stress. Molecular Psychiatry journal. Macmillan
MICHAEL T. LIN & M. FLINT BEAL. (2006). Mitochondrial dysfunction and oxidative stress
in neurodegenerative diseases. Nature:. international weekly journal
GRACE J.KIM, KRISH C &WILLIAM F.MORGAN. (2013). Mitochondrial dysfunction, persistently elevated levels of reactive oxygen species and radiation-induced genomic instability:
a review: Mutogenesis, Oxford journal
CDC. (2014a). Chronic Fatigue Syndrome (CFS): Symptoms. Centers for Disease Control and
CDC. (2014b). Chronic Fatigue Syndrome (CFS): Management of CFS. Centers for Disease
Control and Prevention (CDC).
COOPER, C., & MILLER, J. (2010). Integrative Therapies for Fibromyalgia, Chronic Fatigue
Syndrome, & Myofascial Pain: The Mind Body Connection.
DUCHENE, L. (2014). Mitochondrial Dysfunction, Post-Exertional Malaise and CFS/ME. Massachusetts CFIDS/ME & FM Association.
FIBRO FRIENDS. (2013). Chronic Fatigue Syndrome: Cardiovascular Abnormalities in
Chronic Fatigue Syndrome. Fibro Friends Online.
FILLER, K., LYON, D., BENNETT, J., MCCAIN, N., ELSWICK, R., LUKKAHATAI, N., & SALIGAN, L.N. (2014). Association of Mitochondrial Dysfunction and Fatigue: A Review of
the Literature. BBA Clinical. Vol. 1, pp.12-23.
FIONA M. & MARK R. C (2010). Mitochondrial dysfunction in a cell culture model of familial
amyotrophic lateral sclerosis. Brain: journal of neurology
GRANT, E.C.G. (2013). People Want to Learn as Much as Possible from the PACE Trial for
Chronic Fatigue Syndrome. BMJ Open Access.
HALSTEAD, R. (2014). Bay Area Pharmaceutical Company Develps Treatment for Chronic
Fatigue Syndrome. San Jose Mercury News/Health.
HOUDENHOVE, B.V., EEDE, F.V.D., & LUYTEN, P. (2008). Does Hypothalamic-Pituitary-Adrenal Axis Hypofunction in Chronic Fatigue Syndrome Reflect a ‘Crash’ in the Stress
System? Medical Hypotheses.
JOHNSON, C. (2013). Looking For Answers to Chronic Fatigue Syndrome. Health Rising Online. Landa, J. (2012). How To Combat Stress From Adrenal Fatigue. Fox News Online.
LOGAN, A.C., & WONG, C. (2001). Chronic Fatigue Syndrome: Oxidative Stress and Dietary
Modifications. Alternative Medicine Review
MAYO CLINIC. (2014). Chronic Fatigue Syndrome. Mayo Clinic Online.
MINOCHA, A. (2009). Probiotics for Preventive Health. Nutrition in Clinical Practice (NCP). MYHILL, S., BOOTH, N.E., & MCLAREN-HOWARD, J. (2009). Chronic Fatigue Syndrome and Mitochondrial Dysfunction. International Journal of Clinical and Experimental Medicine
NHS. (2013). Chronic Fatigue Syndrome – Treatment. National Health Service (NHS) Online. NYT. (2008). Chronic Fatigue In-Depth Report. The New York Times Online (NYT).
STEEFEL, L. (2011). What Nurses Know…Chronic Fatigue Syndrome.
TWISK, F.N.M. (2014). The Status of and Future Research into Myalgic Encephalomyelitis and Chronic Fatigue Syndrome: The Need of Accurate Diagnosis, Objective Assessment, and
Acknowledging Biological and Clinical Subgroups. Frontiers in Science.
USDVA. (2014). Chronic Fatigue Syndrome in Gulf War Veterans. U.S. Department of Veteran
WERBACH, M.R. (2000). Nutritional Strategies for Treating Chronic Fatigue Syndrome.
Alternative Medicine Review.
WHRC. (2011). Body Area and Organ Dysfunctions Found in CFS/FMS. Woodlands Healing Research Center (WJRC).
Please type your essay title, choose your document type, enter your email and we send you essay samples